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A Multitasking Vanadium-Dependent Chloroperoxidase as an Inspiration for the Chemical Synthesis of the Merochlorins()

The vanadium-dependent chloroperoxidase Mcl24 was discovered to mediate a complex series of unprecedented transformations in the biosynthesis of the merochlorin meroterpenoid antibiotics. In particular, a site-selective naphthol chlorination is followed by a sequence of oxidative dearomatization/ter...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Diethelm, Stefan, Teufel, Robin, Kaysser, Leonard, Moore, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226426/
https://ncbi.nlm.nih.gov/pubmed/25147132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405696
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