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One-pot Enzymatic Synthesis of Merochlorin A and B()

The polycyclic merochlorin A and B are complex halogenated meroterpenoid natural products with significant antibacterial activities that are produced by the marine bacterium Streptomyces sp. strain CNH-189. Here we employ heterologously produced enzymes and chemical synthesis to fully reconstitute t...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Teufel, Robin, Kaysser, Leonard, Villaume, Matthew T., Diethelm, Stefan, Carbullido, Mary K., Baran, Phil S., Moore, Bradley S.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229033/
https://ncbi.nlm.nih.gov/pubmed/25115835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405694
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