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Polycystin-1 Cleavage and the Regulation of Transcriptional Pathways

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of end stage renal disease, affecting ~1 in 1,000 people. The disease is characterized by the development of numerous large fluid filled renal cysts over the course of decades. These cysts compress the surrounding...

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Autors principals: Merrick, David, Bertuccio, Claudia A., Chapin, Hannah C., Lal, Mark, Chauvet, Veronique, Caplan, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844055/
https://ncbi.nlm.nih.gov/pubmed/23824180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2548-y
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