Microtubule-associated protein tau is essential for long-term depression in the hippocampus

The microtubule-associated protein tau is a principal component of neurofibrillary tangles, and has been identified as a key molecule in Alzheimer's disease and other tauopathies. However, it is unknown how a protein that is primarily located in axons is involved in a disease that is believed t...

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Detalhes bibliográficos
Main Authors: Kimura, Tetsuya, Whitcomb, Daniel J., Jo, Jihoon, Regan, Philip, Piers, Thomas, Heo, Seonghoo, Brown, Christopher, Hashikawa, Tsutomu, Murayama, Miyuki, Seok, Heon, Sotiropoulos, Ioannis, Kim, Eunjoon, Collingridge, Graham L., Takashima, Akihiko, Cho, Kwangwook
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Part III: Synaptic plasticity and brain disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843876/
https://ncbi.nlm.nih.gov/pubmed/24298146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0144
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