Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD

Tau is required for the induction of long-term depression (LTD) of synaptic transmission in the hippocampus. Here we probe the role of tau in LTD, finding that an AMPA receptor internalization mechanism is impaired in tau KO mice, and that LTD causes specific phosphorylation at the serine 396 and 40...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Regan, Philip, Piers, Thomas, Yi, Jee-Hyun, Kim, Dong-Hyun, Huh, Seonghoo, Park, Se Jin, Ryu, Jong Hoon, Whitcomb, Daniel J., Cho, Kwangwook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389589/
https://ncbi.nlm.nih.gov/pubmed/25810511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2842-14.2015
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