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Structural basis of the Axin–adenomatous polyposis coli interaction
Axin and the adenomatous polyposis coli (APC) tumor suppressor protein are components of the Wnt/Wingless growth factor signaling pathway. In the absence of Wnt signal, Axin and APC regulate cytoplasmic levels of the proto-oncogene β-catenin through the formation of a large complex containing these...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384355/ https://ncbi.nlm.nih.gov/pubmed/10811618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.10.2270 |
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