Structural basis for the recognition of Asef by adenomatous polyposis coli

Adenomatous polyposis coli (APC) regulates cell-cell adhesion and cell migration through activating the APC-stimulated guanine nucleotide-exchange factor (GEF; Asef), which is usually autoinhibited through the binding between its Src homology 3 (SH3) and Dbl homology (DH) domains. The APC-activated...

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Detalhes bibliográficos
Main Authors: Zhang, Zhenyi, Chen, Leyi, Gao, Lei, Lin, Kui, Zhu, Liang, Lu, Yang, Shi, Xiaoshan, Gao, Yuan, Zhou, Jing, Xu, Ping, Zhang, Jian, Wu, Geng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271586/
https://ncbi.nlm.nih.gov/pubmed/21788986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.119
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