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Molecular Basis for the Recognition of Adenomatous Polyposis Coli by the Discs Large 1 Protein
The human Discs Large 1 (DLG1) protein uses two of its three PDZ domains to interact with the C-terminal peptide of the Adenomatous Polyposis Coli (APC) tumor suppressor protein. The DLG1/APC complex inhibits the cell cycle progression from the G0/G1 to the S phase, regulates epithelial cell migrati...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157396/ https://ncbi.nlm.nih.gov/pubmed/21858148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023507 |
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