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Adenomatous Polyposis Coli Gene Mutations in 22 Chinese Pedigrees with Familial Adenomatous Polyposis

BACKGROUND: Familial adenomatous polyposis (FAP), which has a very high tendency of progression to colorectal cancer, is mainly caused by mutations of the adenomatous polyposis coli (APC) gene. This study systematically screened the APC mutations and observed the correlation of APC mutations with cl...

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Vydáno v:Med Sci Monit
Hlavní autoři: Wang, Dan, Zhang, Zhao, Li, Yuwei, Xu, Chen, Yu, Yongjun, Li, Mingsen, Chen, Chao, Zhang, Xipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542301/
https://ncbi.nlm.nih.gov/pubmed/31113927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913911
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