Molecular Basis for the Recognition of Adenomatous Polyposis Coli by the Discs Large 1 Protein

The human Discs Large 1 (DLG1) protein uses two of its three PDZ domains to interact with the C-terminal peptide of the Adenomatous Polyposis Coli (APC) tumor suppressor protein. The DLG1/APC complex inhibits the cell cycle progression from the G0/G1 to the S phase, regulates epithelial cell migrati...

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Bibliografiske detaljer
Main Authors: Zhang, Zhenyi, Li, Hua, Chen, Leyi, Lu, Xingyu, Zhang, Jian, Xu, Ping, Lin, Kui, Wu, Geng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157396/
https://ncbi.nlm.nih.gov/pubmed/21858148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023507
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