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Synovial perlecan is required for osteophyte formation in knee osteoarthritis
The osteophyte associated with osteoarthritis (OA) is a bony outgrowth formed at the margins of the affected joint through endochondral ossification-like processes. However, the mechanism of osteophyte formation and its pathogenesis are unclear. Perlecan (Hspg2), a heparan sulfate proteoglycan, is e...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843243/ https://ncbi.nlm.nih.gov/pubmed/23339896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.01.004 |
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