Histone Lysine-specific Demethylase 1 (LSD1) Protein Is Involved in Sal-like Protein 4 (SALL4)-mediated Transcriptional Repression in Hematopoietic Stem Cells

The stem cell protein SALL4 plays a critical role in hematopoiesis by regulating the cell fate. In primitive hematopoietic precursors, it activates or represses important genes via recruitment of various epigenetic factors such as DNA methyltransferases, and histone deacylases. Here, we demonstrate...

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Autores principales: Liu, Li, Souto, Joseph, Liao, Wenbin, Jiang, Yongping, Li, Yangqiu, Nishinakamura, Ryuichi, Huang, Suming, Rosengart, Todd, Yang, Vincent W., Schuster, Michael, Ma, Yupo, Yang, Jianchang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843083/
https://ncbi.nlm.nih.gov/pubmed/24163373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.506568
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