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Stem Cell Gene SALL4 Suppresses Transcription through Recruitment of DNA Methyltransferases

The stem cell protein SALL4 plays a vital role in maintaining stem cell identity and governing stem cell self-renewal through transcriptional repression. To explore SALL4-mediated mechanisms involved in transcriptional repression, we investigated DNA modifications underlying its regulatory activitie...

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Autores principales: Yang, Jianchang, Corsello, Tyler R., Ma, Yupo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265879/
https://ncbi.nlm.nih.gov/pubmed/22128185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308734
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