Histone Lysine-specific Demethylase 1 (LSD1) Protein Is Involved in Sal-like Protein 4 (SALL4)-mediated Transcriptional Repression in Hematopoietic Stem Cells

The stem cell protein SALL4 plays a critical role in hematopoiesis by regulating the cell fate. In primitive hematopoietic precursors, it activates or represses important genes via recruitment of various epigenetic factors such as DNA methyltransferases, and histone deacylases. Here, we demonstrate...

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Bibliografiske detaljer
Main Authors: Liu, Li, Souto, Joseph, Liao, Wenbin, Jiang, Yongping, Li, Yangqiu, Nishinakamura, Ryuichi, Huang, Suming, Rosengart, Todd, Yang, Vincent W., Schuster, Michael, Ma, Yupo, Yang, Jianchang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843083/
https://ncbi.nlm.nih.gov/pubmed/24163373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.506568
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