Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in Vivo

Differentiated retinal pigmented epithelial (RPE) cells have been obtained from human induced pluripotent stem (hiPS) cells. However, the visual (retinoid) cycle in hiPS-RPE cells has not been adequately examined. Here we determined the expression of functional visual cycle enzymes in hiPS-RPE cells...

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Autores principales: Maeda, Tadao, Lee, Mee Jee, Palczewska, Grazyna, Marsili, Stefania, Tesar, Paul J., Palczewski, Krzysztof, Takahashi, Masayo, Maeda, Akiko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843063/
https://ncbi.nlm.nih.gov/pubmed/24129572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518571
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