Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in Vivo

Differentiated retinal pigmented epithelial (RPE) cells have been obtained from human induced pluripotent stem (hiPS) cells. However, the visual (retinoid) cycle in hiPS-RPE cells has not been adequately examined. Here we determined the expression of functional visual cycle enzymes in hiPS-RPE cells...

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Main Authors: Maeda, Tadao, Lee, Mee Jee, Palczewska, Grazyna, Marsili, Stefania, Tesar, Paul J., Palczewski, Krzysztof, Takahashi, Masayo, Maeda, Akiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843063/
https://ncbi.nlm.nih.gov/pubmed/24129572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518571
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