Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in Vivo

Differentiated retinal pigmented epithelial (RPE) cells have been obtained from human induced pluripotent stem (hiPS) cells. However, the visual (retinoid) cycle in hiPS-RPE cells has not been adequately examined. Here we determined the expression of functional visual cycle enzymes in hiPS-RPE cells...

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Autori principali: Maeda, Tadao, Lee, Mee Jee, Palczewska, Grazyna, Marsili, Stefania, Tesar, Paul J., Palczewski, Krzysztof, Takahashi, Masayo, Maeda, Akiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843063/
https://ncbi.nlm.nih.gov/pubmed/24129572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518571
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