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Progranulin: At the interface of neurodegenerative and metabolic diseases
Progranulin is a widely expressed, cysteine-rich, secreted glycoprotein originally discovered for its growth factor–like properties. Its subsequent identification as a causative gene for frontotemporal dementia (FTD), a devastating early-onset neurodegenerative disease, has catalyzed a surge of new...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842380/ https://ncbi.nlm.nih.gov/pubmed/24035620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2013.08.003 |
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