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Secreted Progranulin Is a Homodimer and Is Not a Component of High Density Lipoproteins (HDL)
Progranulin is a secreted glycoprotein, and the GRN gene is mutated in some cases of frontotemporal dementia. Progranulin has also been implicated in cell growth, wound healing, inflammation, and cancer. We investigated the molecular nature of secreted progranulin and provide evidence that progranul...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605681/ https://ncbi.nlm.nih.gov/pubmed/23364791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441949 |
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