Hepatic Deficiency of Low Density Lipoprotein Receptor-related Protein-1 Reduces High Density Lipoprotein Secretion and Plasma Levels in Mice

The low density lipoprotein receptor-related protein-1 (LRP1) is known to serve as a chylomicron remnant receptor in the liver responsible for the binding and plasma clearance of apolipoprotein E-containing lipoproteins. Previous in vitro studies have provided evidence to suggest that LRP1 expressio...

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Main Authors: Basford, Joshua E., Wancata, Lauren, Hofmann, Susanna M., Silva, R. A. Gangani D., Davidson, W. Sean, Howles, Philip N., Hui, David Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075654/
https://ncbi.nlm.nih.gov/pubmed/21343303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229369
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