A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

Frontotemporal lobar degeneration is a progressive neurodegenerative syndrome that is the second most common cause of early-onset dementia. Mutations in the progranulin gene are a major cause of familial frontotemporal lobar degeneration [Baker M, et al. (2006) Nature 442:916–919 and Cruts M, et al....

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Bibliografiska uppgifter
Huvudupphovsmän: Kao, Aimee W., Eisenhut, Robin J., Martens, Lauren Herl, Nakamura, Ayumi, Huang, Anne, Bagley, Josh A., Zhou, Ping, de Luis, Alberto, Neukomm, Lukas J., Cabello, Juan, Farese, Robert V., Kenyon, Cynthia
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060230/
https://ncbi.nlm.nih.gov/pubmed/21368173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100650108
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