A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

Frontotemporal lobar degeneration is a progressive neurodegenerative syndrome that is the second most common cause of early-onset dementia. Mutations in the progranulin gene are a major cause of familial frontotemporal lobar degeneration [Baker M, et al. (2006) Nature 442:916–919 and Cruts M, et al....

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Detalhes bibliográficos
Main Authors: Kao, Aimee W., Eisenhut, Robin J., Martens, Lauren Herl, Nakamura, Ayumi, Huang, Anne, Bagley, Josh A., Zhou, Ping, de Luis, Alberto, Neukomm, Lukas J., Cabello, Juan, Farese, Robert V., Kenyon, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060230/
https://ncbi.nlm.nih.gov/pubmed/21368173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100650108
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