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Biopterin Metabolism and eNOS Expression during Hypoxic Pulmonary Hypertension in Mice
Tetrahydrobiopterin (BH(4)), which fosters the formation of and stabilizes endothelial NO synthase (eNOS) as an active dimer, tightly regulates eNOS coupling / uncoupling. Moreover, studies conducted in genetically-modified models demonstrate that BH(4) pulmonary deficiency is a key determinant in t...
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| Hoofdauteurs: | , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842263/ https://ncbi.nlm.nih.gov/pubmed/24312428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082594 |
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