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Modeling of Biopterin Dependent Pathways of eNOS for Nitric Oxide & Superoxide Production
Endothelial dysfunction is associated with increase in oxidative stress and low NO bioavailability. The eNOS uncoupling is considered an important factor in endothelial cell oxidative stress. Under increased oxidative stress, the eNOS cofactor BH(4) is oxidized to dihydrobiopterin (BH(2)), which com...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184605/ https://ncbi.nlm.nih.gov/pubmed/21742028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.06.009 |
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