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Endothelial NO and O(2)(•−) Production Rates Differentially Regulate Oxidative, Nitroxidative and Nitrosative Stress in the Microcirculation
Endothelial dysfunction causes an imbalance in endothelial NO and O(2)(•−) production rates and increased peroxynitrite formation. Peroxynitrite and its decomposition products cause multiple deleterious effects including tyrosine nitration of proteins, superoxide dismutase (SOD) inactivation and tis...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051226/ https://ncbi.nlm.nih.gov/pubmed/23639567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.024 |
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