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Endothelial NO and O(2)(•−) Production Rates Differentially Regulate Oxidative, Nitroxidative and Nitrosative Stress in the Microcirculation

Endothelial dysfunction causes an imbalance in endothelial NO and O(2)(•−) production rates and increased peroxynitrite formation. Peroxynitrite and its decomposition products cause multiple deleterious effects including tyrosine nitration of proteins, superoxide dismutase (SOD) inactivation and tis...

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Bibliografiske detaljer
Main Authors: Kar, Saptarshi, Kavdia, Mahendra
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051226/
https://ncbi.nlm.nih.gov/pubmed/23639567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.024
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