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Metabolic imaging using two-photon excited NADH intensity and fluorescence lifetime imaging

Metabolism and mitochondrial dysfunction are known to be involved in many different disease states. We have employed two-photon fluorescence imaging of intrinsic mitochondrial reduced nicotinamide adenine dinucleotide (NADH) to quantify the metabolic state of several cultured cell lines, multicell t...

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Detalhes bibliográficos
Main Authors: Vergen, Jorge, Hecht, Clifford, Zholudeva, Lyandysha V., Marquardt, Meg M., Hallworth, Richard, Nichols, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842212/
https://ncbi.nlm.nih.gov/pubmed/22832200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1431927612000529
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