In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH

Minimally invasive, specific measurement of cellular energy metabolism is crucial for understanding cerebral pathophysiology. Here, we present high-resolution, in vivo observations of autofluorescence lifetime as a biomarker of cerebral energy metabolism in exposed rat cortices. We describe a custom...

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Библиографические подробности
Главные авторы: Yaseen, Mohammad A., Sakadžić, Sava, Wu, Weicheng, Becker, Wolfgang, Kasischke, Karl A., Boas, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: Optical Society of America 2013
Предметы:
Functional Imaging
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567717/
https://ncbi.nlm.nih.gov/pubmed/23412419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.4.000307
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