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Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence

The brain's ability to function at high levels of metabolic demand depends on continuous oxygen supply through blood flow and tissue oxygen diffusion. Here we present a visualized experimental and methodological protocol to directly visualize microregional tissue hypoxia and to infer perivascul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Polesskaya, Oksana, Sun, Anita, Salahura, Gheorghe, Silva, Jharon N., Dewhurst, Stephen, Kasischke, Karl
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376929/
https://ncbi.nlm.nih.gov/pubmed/22370971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3466
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