Two-photon excited fluorescence lifetime imaging and spectroscopy of melanins in vitro and in vivo

Changes in the amounts of cellular eumelanin and pheomelanin have been associated with carcinogenesis. The goal of this work is to develop methods based on two-photon-excited-fluorescence (TPEF) for measuring relative concentrations of these compounds. We acquire TPEF emission spectra ([Formula: see...

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Bibliographic Details
Main Authors: Krasieva, Tatiana B., Stringari, Chiara, Liu, Feng, Sun, Chung-Ho, Kong, Yu, Balu, Mihaela, Meyskens, Frank L., Gratton, Enrico, Tromberg, Bruce J.
Format: Artigo
Language:Inglês
Published: Society of Photo-Optical Instrumentation Engineers 2012
Subjects:
Special Section Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595716/
https://ncbi.nlm.nih.gov/pubmed/23235925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.18.3.031107
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