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Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains

High metabolic activity and low levels of antioxidant enzymes make neurons particularly prone to damage by reactive oxygen species. Thus, repair of oxidative DNA damage is essential for normal brain function. Base excision repair is the major pathway for repair of oxidative DNA damage, and is initia...

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Bibliografski detalji
Glavni autori: Rolseth, Veslemøy, Rundén-Pran, Elise, Luna, Luisa, McMurray, Cynthia, Bjørås, Magnar, Ottersen, Ole Petter
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842036/
https://ncbi.nlm.nih.gov/pubmed/18603019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.06.007
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