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Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroiminohydantoin and guanidinohydantoin

Base excision repair is the major pathway for removal of oxidative DNA base damage. This pathway is initiated by DNA glycosylases, which recognize and excise damaged bases from DNA. In this work, we have purified the glycosylase domain (GD) of human DNA glycosylase NEIL3. The substrate specificity h...

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Main Authors:	Krokeide, Silje Z., Laerdahl, Jon K., Salah, Medya, Luna, Luisa, Cederkvist, F. Henning, Fleming, Aaron M., Burrows, Cynthia J., Dalhus, Bjørn, Bjørås, Magnar
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2013
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3840045/ https://ncbi.nlm.nih.gov/pubmed/23755964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.026
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Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroiminohydantoin and guanidinohydantoin

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