Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroiminohydantoin and guanidinohydantoin

Base excision repair is the major pathway for removal of oxidative DNA base damage. This pathway is initiated by DNA glycosylases, which recognize and excise damaged bases from DNA. In this work, we have purified the glycosylase domain (GD) of human DNA glycosylase NEIL3. The substrate specificity h...

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Detalhes bibliográficos
Main Authors: Krokeide, Silje Z., Laerdahl, Jon K., Salah, Medya, Luna, Luisa, Cederkvist, F. Henning, Fleming, Aaron M., Burrows, Cynthia J., Dalhus, Bjørn, Bjørås, Magnar
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840045/
https://ncbi.nlm.nih.gov/pubmed/23755964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.026
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