Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.

Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and clopimozide, inhibit [3H]nitrendipine binding with IC50 values of 13-30 nM. This inhibition involves receptors for the verapamil/prenylamine class of calcium channel anta...

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Bibliografiske detaljer
Main Authors: Gould, R J, Murphy, K M, Reynolds, I J, Snyder, S H
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384201/
https://ncbi.nlm.nih.gov/pubmed/6136040
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