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Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.
Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and clopimozide, inhibit [3H]nitrendipine binding with IC50 values of 13-30 nM. This inhibition involves receptors for the verapamil/prenylamine class of calcium channel anta...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1983
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6136040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.16.5122 |
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