Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.

Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and clopimozide, inhibit [3H]nitrendipine binding with IC50 values of 13-30 nM. This inhibition involves receptors for the verapamil/prenylamine class of calcium channel anta...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gould, R J, Murphy, K M, Reynolds, I J, Snyder, S H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1983
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6136040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.16.5122
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