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Neuroleptics of the diphenylbutylpiperidine series are potent calcium channel inhibitors.

[3H]Fluspirilene, a neuroleptic molecule of the diphenylbutylpiperidine series, binds to skeletal muscle transverse tubule membranes with a high affinity corresponding to a Kd of 0.11 +/- 0.04 nM, A 1:1 stoichiometry was found between [3H]fluspirilene binding and the binding of (-)-[3H]desmethoxyver...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Galizzi, J P, Fosset, M, Romey, G, Laduron, P, Lazdunski, M
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1986
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2429309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7513
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