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Neuroleptics of the diphenylbutylpiperidine series are potent calcium channel inhibitors.
[3H]Fluspirilene, a neuroleptic molecule of the diphenylbutylpiperidine series, binds to skeletal muscle transverse tubule membranes with a high affinity corresponding to a Kd of 0.11 +/- 0.04 nM, A 1:1 stoichiometry was found between [3H]fluspirilene binding and the binding of (-)-[3H]desmethoxyver...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2429309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7513 |
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