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The presence in pig brain of an endogenous equivalent of apamin, the bee venom peptide that specifically blocks Ca2+-dependent K+ channels.

An apamin-like factor has been isolated from pig brain after extraction of the tissue and purification on sulfopropyl-Sephadex C-25 and on reversed-phase high pressure liquid chromatography. The apamin-like factor has the following properties: (i) it prevents 125I-labeled apamin binding to its speci...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Fosset, M, Schmid-Antomarchi, H, Hugues, M, Romey, G, Lazdunski, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392112/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6095277/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.22.7228
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