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Discovery of Staphylococcus aureus Sortase A Inhibitors Using Virtual Screening and the Relaxed Complex Scheme
Staphylococcus aureus is the leading cause of hospital-acquired infections in the United States. The emergence of multi-drug resistant strains of S. aureus has created an urgent need for new antibiotics. S. aureus uses the sortase A (SrtA) enzyme to display surface virulence factors suggesting that...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3841297/ https://ncbi.nlm.nih.gov/pubmed/23701677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12167 |
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