De Novo Design and Synthesis of Ultra-Short Peptidomimetic Antibiotics Having Dual Antimicrobial and Anti-Inflammatory Activities

BACKGROUND: Much attention has been focused on the design and synthesis of potent, cationic antimicrobial peptides (AMPs) that possess both antimicrobial and anti-inflammatory activities. However, their development into therapeutic agents has been limited mainly due to their large size (12 to 50 res...

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Auteurs principaux: Murugan, Ravichandran N., Jacob, Binu, Ahn, Mija, Hwang, Eunha, Sohn, Hoik, Park, Hyo-Nam, Lee, Eunjung, Seo, Ji-Hyung, Cheong, Chaejoon, Nam, Ky-Youb, Hyun, Jae-Kyung, Jeong, Ki-Woong, Kim, Yangmee, Shin, Song Yub, Bang, Jeong Kyu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841161/
https://ncbi.nlm.nih.gov/pubmed/24302996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080025
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