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Transcriptional super-enhancers connected to cell identity and disease

Super-enhancers are large clusters of transcriptional enhancers that drive expression of genes that define cell identity. Improved understanding of the roles super-enhancers play in biology would be afforded by knowing the constellation of factors that constitute these domains and by identifying sup...

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Podrobná bibliografie
Hlavní autoři: Hnisz, Denes, Abraham, Brian J., Lee, Tong Ihn, Lau, Ashley, Saint-André, Violaine, Sigova, Alla A., Hoke, Heather, Young, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841062/
https://ncbi.nlm.nih.gov/pubmed/24119843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.053
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