Spontaneous Generation of Infectious Prion Disease in Transgenic Mice

We generated transgenic mice expressing bovine cellular prion protein (PrP(C)) with a leucine substitution at codon 113 (113L). This protein is homologous to human protein with mutation 102L, and its genetic link with Gerstmann–Sträussler–Scheinker syndrome has been established. This mutation in bov...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Torres, Juan-María, Castilla, Joaquín, Pintado, Belén, Gutiérrez-Adan, Alfonso, Andréoletti, Olivier, Aguilar-Calvo, Patricia, Arroba, Ana-Isabel, Parra-Arrondo, Beatriz, Ferrer, Isidro, Manzanares, Jorge, Espinosa, Juan-Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840888/
https://ncbi.nlm.nih.gov/pubmed/24274622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1912.130106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados