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Small-Molecule Allosteric Activation of Human Glucokinase in the Absence of Glucose
[Image: see text] Synthetic allosteric activators of human glucokinase are receiving considerable attention as potential diabetes therapeutic agents. Although their mechanism of action is not fully understood, structural studies suggest that activator association requires prior formation of a binary...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical Society
2013
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840467/ https://ncbi.nlm.nih.gov/pubmed/24294411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400061x |
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