Degradation of cIAPs contributes to hepatocyte lipoapoptosis

Hepatocyte apoptosis is a hallmark of nonalcoholic steatohepatitis. We have previously observed that the saturated free fatty acids (FFAs) induce hepatocyte apoptosis in part via a death receptor 5 (DR5)-mediated signaling pathway. Cellular inhibitor of apoptosis protein 1 and 2 (cIAP-1 and cIAP-2)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Akazawa, Yuko, Guicciardi, Maria Eugenia, Cazanave, Sophie C., Bronk, Steven F., Werneburg, Nathan W., Kakisaka, Keisuke, Nakao, Kazuhiko, Gores, Gregory J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
Soggetti:
Call for Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840239/
https://ncbi.nlm.nih.gov/pubmed/24008361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00111.2013
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi