Aurora Kinase A Promotes Inflammation and Tumorigenesis in Mice and Human Gastric Neoplasia

BACKGROUND & AIMS: Chronic inflammation contributes to the pathogenesis of gastric tumorigenesis. The Aurora kinase A gene (AURKA) is frequently amplified and overexpressed in gastrointestinal cancers. We investigated the roles of AURKA in inflammation and gastric tumorigenesis. METHODS: We used...

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Main Authors: Katsha, Ahmed, Soutto, Mohammed, Sehdev, Vikas, Peng, Dunfa, Washington, M. Kay, Piazuelo, M. Blanca, Tantawy, Mohammed N., Manning, H. Charles, Lu, Pengcheng, Shyr, Yu, Ecsedy, Jeffrey, Belkhiri, Abbes, El-Rifai, Wael
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840093/
https://ncbi.nlm.nih.gov/pubmed/23993973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.08.050
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