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Stemming Danger with Golgified BAX
In this issue of Molecular Cell, Dumitru et al. (2012) report that hES cells localize a conformationally activated form of proapoptotic BAX to the trans Golgi network, a previously unanticipated launch pad for mitochondrial assault in response to DNA damage.
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839817/ https://ncbi.nlm.nih.gov/pubmed/22681883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.034 |
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