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BAX Unleashed: The Biochemical Transformation of an Inactive Cytosolic Monomer into a Toxic Mitochondrial Pore

BAX, the BCL-2-associated X protein, is a cardinal pro-apoptotic member of the BCL-2 family, which regulates the critical balance between cellular life and death. Because so many medical conditions can be categorized as diseases of either too many or too few cells, dissecting the biochemistry of BCL...

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Bibliografiske detaljer
Main Authors: Walensky, Loren D., Gavathiotis, Evripidis
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454508/
https://ncbi.nlm.nih.gov/pubmed/21978892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.08.009
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