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BAX Unleashed: The Biochemical Transformation of an Inactive Cytosolic Monomer into a Toxic Mitochondrial Pore

BAX, the BCL-2-associated X protein, is a cardinal pro-apoptotic member of the BCL-2 family, which regulates the critical balance between cellular life and death. Because so many medical conditions can be categorized as diseases of either too many or too few cells, dissecting the biochemistry of BCL...

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Detalhes bibliográficos
Main Authors: Walensky, Loren D., Gavathiotis, Evripidis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454508/
https://ncbi.nlm.nih.gov/pubmed/21978892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.08.009
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