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BAX Unleashed: The Biochemical Transformation of an Inactive Cytosolic Monomer into a Toxic Mitochondrial Pore

BAX, the BCL-2-associated X protein, is a cardinal pro-apoptotic member of the BCL-2 family, which regulates the critical balance between cellular life and death. Because so many medical conditions can be categorized as diseases of either too many or too few cells, dissecting the biochemistry of BCL...

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Dettagli Bibliografici
Autori principali: Walensky, Loren D., Gavathiotis, Evripidis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454508/
https://ncbi.nlm.nih.gov/pubmed/21978892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.08.009
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