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Cheating Death: New Molecules Block BAX
BAX is a formidable BCL-2 family protein that executes cellular suicide in response to physiologic and pathologic stress. A new article in Nature Chemical Biology (Garner et al. https://doi.org/10.1038/s41589-018-0223-0) reports small molecules that inhibit the conformational activation of BAX, info...
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| Publicado no: | Trends Mol Med |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255386/ https://ncbi.nlm.nih.gov/pubmed/30852140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.02.008 |
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