B cells are critical for autoimmune pathology in Scurfy mice

Impaired regulatory T-cell function results in a severe chronic autoimmune disease affecting multiple organs in Scurfy mice and humans with the immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome. Previous studies have shown that T helper cells but not cytotoxic T cells a...

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Bibliografiska uppgifter
Huvudupphovsmän: Aschermann, Susanne, Lehmann, Christian H. K., Mihai, Sidonia, Schett, Georg, Dudziak, Diana, Nimmerjahn, Falk
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839754/
https://ncbi.nlm.nih.gov/pubmed/24194550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313547110
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