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Changing hydration level in an internal cavity modulates the proton affinity of a key glutamate in cytochrome c oxidase
Cytochrome c oxidase contributes to the transmembrane proton gradient by removing two protons from the high-pH side of the membrane each time the binuclear center active site is reduced. One proton goes to the binuclear center, whereas the other is pumped to the low-pH periplasmic space. Glutamate 2...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839721/ https://ncbi.nlm.nih.gov/pubmed/24198332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313908110 |
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