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Microscopic basis for kinetic gating in cytochrome c oxidase: insights from QM/MM analysis

Understanding the mechanism of vectorial proton pumping in biomolecules requires establishing the microscopic basis for the regulation of both thermodynamic and kinetic features of the relevant proton transfer steps. For the proton pump cytochrome c oxidase, while the regulation of thermodynamic dri...

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Pubblicato in:Chem Sci
Autori principali: Goyal, Puja, Yang, Shuo, Cui, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321873/
https://ncbi.nlm.nih.gov/pubmed/25678950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc01674b
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